Exploring the concept of inflammatory angiogenesis in keratocystic odontogenic tumor
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چکیده
منابع مشابه
Exploring the concept of “inflammatory angiogenesis” in keratocystic odontogenic tumor
OBJECTIVE The aim of the present study was to investigate the role of inflammation in angiogenesis of keratocystic odontogenic tumor (KCOT). STUDY DESIGN Twenty inflamed and 20 non-inflamed KCOTs were selected based on quantitative scoring of inflammation which was also applied on 20 radicular cysts. Microvessel density was assessed in all samples using CD34 antibody and angiogenesis was comp...
متن کاملAngiogenesis: A Critical Role in Locally Aggressive Behavior of Keratocystic Odontogenic Tumor
Introduction: Odontogenic cysts are osteodestructive lesions affecting the jaws. Odontogenic keratocyst is an odontogenic cyst with highly aggressive features. Multicystic ameloblastoma is a benign epithelial odontogenic tumor with more aggressive behavior than dentigerous cyst and odontogenic keratocyst. Invasion and metastasis of tumors require increased blood vessels during tumorigenesis. Th...
متن کاملThe Evaluation of Diagnostic Values of RelatedMarkers in Keratocystic Odontogenic Tumor’s Angiogenesis
Introduction: Odontogenic tumors include a variety of lesions that are classified from hamartomas to benign and malignant neoplasms. Angiogenesis process helps neoplastic tissue to gain an adequate supply of oxygen and also to remove the waste products. Mean Vessel Density (MVD) evaluation is a common method for assessing angiogenesis by using different markers. To the best of our knowledge, t...
متن کاملExpression of CD105 in tumor angiogenesis a comparative study (ameloblastoma, keratocystic odontogenic tumor and dentigerous cyst)
BACKGROUND Demonstrate the expression of CD105 (angiogenetic marker) in ameloblastoma (AM), keratocystic odontogenic tumor (KCOT) and dentigerous cyst (DC). MATERIAL AND METHODS Assessment of microvessel density (MVD) in 70 cases, including 20 KCOT, 20 DC and 20 solid AMs. Assessment of MVD should be done as the mean number of microvessels per high-power-field. RESULTS AM and KCOT demonstra...
متن کاملTumor angiogenesis: role in locally aggressive biological behavior of ameloblastoma and keratocystic odontogenic tumor.
BACKGROUND The purpose of this study was to assess and compare angiogenesis in ameloblastoma, keratocystic odontogenic tumors, dentigerous cysts, and normal oral mucosa. METHODS Angiogenesis was assessed in 28 ameloblastoma-36 keratocystic odontogenic tumors, 28 dentigerous cysts, and 19 normal oral mucosa by measuring the mean vascular density (MVD), total vascular area (TVA) and mean vascul...
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ژورنال
عنوان ژورنال: Medicina Oral Patología Oral y Cirugia Bucal
سال: 2013
ISSN: 1698-6946
DOI: 10.4317/medoral.18351